发明名称 |
Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use |
摘要 |
Sulfoalkyl ether-cyclodextrin (SAE-CD) based pharmaceutical formulations are provided by the present invention. These formulations comprise SAE-CD derivatives and a therapeutic agent, a major portion of which is not complexed to the SAE-CD. The present formulations are advantageously easier to prepare than other SAE-CD based formulations in the art yet provide similar or improved effectiveness. The SAE-CD derivative can be used to modify the bioavailability and/or rate of bioabsorption of therapeutic agents.
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申请公布号 |
US5874418(A) |
申请公布日期 |
1999.02.23 |
申请号 |
US19970851006 |
申请日期 |
1997.05.05 |
申请人 |
CYDEX, INC. |
发明人 |
STELLA, VALENTINO;RAJEWSKI, ROGER A.;MCGINITY, JAMES W. |
分类号 |
A61K9/20;A61K9/28;A61K47/40;C08B37/16;(IPC1-7):A61K31/735;C07H13/12 |
主分类号 |
A61K9/20 |
代理机构 |
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