| 发明名称 |
Vaccine for enhanced production of IgA antibodies |
| 摘要 |
The invention describes compositions and methods for optimizing IgA class switching in B cells. The compositions comprise a multivalent antigen receptor crosslinker, CD40 ligand or lipopolysaccharide, and the cytokines TGF- beta , IL-4, and either IL-5 or IL-2. Methods of using the compositions are also described.
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| 申请公布号 |
US5874085(A) |
申请公布日期 |
1999.02.23 |
| 申请号 |
US19950400322 |
申请日期 |
1995.03.08 |
| 申请人 |
HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE |
发明人 |
MOND, JAMES J.;SNAPPER, CLIFFORD M. |
| 分类号 |
A61K9/08;A61K31/715;A61K35/74;A61K38/00;A61K38/19;A61K38/21;A61K38/22;A61K39/385;A61K39/39;A61P31/12;A61P37/04;A61P43/00;C07K14/535;C07K14/54;C07K16/24;C07K16/42;G01N33/53;G01N33/68;(IPC1-7):A61K39/00;A61K38/18;A61K39/02 |
主分类号 |
A61K9/08 |
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