ANTIBODY TO SMOOTH MUSCLE MYOSIN HEAVY CHAINS

摘要

Using as an immunogen an oligopeptide containing a different portion of the amino acid sequence of isoform SM-l, SM-2 or SM-3 in smooth muscle myosin heavy chains, for example, the C-terminus amino acid sequence, antibodies capable of distinctly recognizing each isoform from other of the smooth muscle myosin heavy chains can be obtained. The antibodies are useful as reagents for tissue staining and also useful as diagnostic reagents of vascular disturbance or arteriosclerosis.