发明名称 NEUES BISHETEROCYCLISCHES DERIVAT UND SALZ UND HYPOGLYKÄMISCHE ZUSAMMENSETZUNG
摘要 <p>A bisheterocyclic compound represented by general formula (I), stereoisomers thereof, tautomers thereof, a pharmaceutically acceptable salt or a pharmaceutically acceptable solvate thereof, a pharmaceutical composition containing the same, and a process for the production thereof. In formula (I), R<1> and R<2> may be the same or different from each other and each represents (II) or (III), R3 represents hydrogen or a protective group, X, Y<1> and Y<2> may be the same or different from one another and each represents oxygen or sulfur, B<1> and B<2> represent each phenylene, B<3> represents phenylene, naphthylene, cyclohexylene or furo[3,2-b]furanylene, L<1> and L<2> represent each -(O)n-A-, n represents 0 or 1, and A represents a single bond or lower alkylene, provided that when n is 1, A represents alkylene and the oxygen atom of each of L<1> and L<2> is bonded to B<3>. The above compounds are useful as a hypoglycemic drug based on the activity of enhancing insulin sensitivity. <CHEM></p>
申请公布号 DE69228122(D1) 申请公布日期 1999.02.18
申请号 DE1992628122 申请日期 1992.07.28
申请人 YAMANOUCHI PHARMACEUTICAL CO., LTD., TOKIO/TOKYO, JP 发明人 NIIGATA, KUNIHIRO 287, NAKABUN 2-CHOME, SAITAMA 362, JP;TAKAHASHI, TAKUMI 5-9, NINOMIYA 2-CHOME, IBARAKI 305, JP;YONEDA, TAKASHI 6-1, AKEBONO 4-CHOME, CHIBA 277, JP;NOSHIRO, OSAMU 2240-79, WAKASHIBACHO, IBARAKI 301, JP;KOIKE, REIKO 1456, OHAZA SHIMOINAYOSHI, NIIHARI-GUN IBARAKI 315, JP;SHIMAYA, AKIYOSHI 5-9, NONOMIYA 2-CHOME, IBARAKI 305, JP
分类号 C07D263/44;C07D277/20;C07D277/34;C07D277/36;C07D493/04;(IPC1-7):C07D263/44;A61K31/42;A61K31/425;C07D417/12;C07D263/46 主分类号 C07D263/44
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