发明名称 SWAINSONINE DERIVATIVES AND METHODS FOR PREPARING THE SAME
摘要 <p>Compounds of formula (I) wherein: R is defined in the specification; each R', independently of the other, is H, acetyl, benzyl, methoxymethyl, tosyl, mesyl, trifluoromesyl, tri(C1-14alkyl)silyl, di(C1-14alkyl)phenylsilyl, diphenyl(C1-14alkyl)silyl, or triphenylsilyl, or both R together form an alkylidene protecting group; R'' is H, acetyl, benzyl, methoxymethyl, tosyl, mesyl, trifluoromesyl, tri(C1-14alkyl)silyl, di(C1-14alkylsilyl)phenylsilyl, diphenyl(C1-14alkyl)silyl, or triphenylsilyl; X is H, C1, Br, or R4 (where R4 is C¿1-22-alkyl?); Y is H, C1, Br, or -CHR?2OH, -CR2R3¿OH, -CH¿2CHR?2OH, -CH¿2?CR?2R3OH, -SR2, -SeR2¿, -OH, -NH¿2, -R?5 (where R?2, R3, and R5¿ are independently or each other C¿1-22?-alkyl); or X and Y together form a covalent bond; A and A' are both H or together A and A' form =O, are useful as anticancer agents and as glycosidase inhibitors.</p>
申请公布号 WO1999007366(A1) 申请公布日期 1999.02.18
申请号 US1998015804 申请日期 1998.08.06
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