发明名称 |
Peptide derivatives |
摘要 |
The present invention relates to a pharmacologically active peptide hormone derivative in which the parent peptide hormone has been modified by introducing either a lipophilic substituent, W, in the N-terminal amino acid or a lipophilic substituent, Z, in the C-terminal amino acid of the parent peptide hormone or an analogue thereof, said lipophilic substituent having from 8 to 40 carbon atoms, has a protracted profile of action.
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申请公布号 |
US5869602(A) |
申请公布日期 |
1999.02.09 |
申请号 |
US19950448219 |
申请日期 |
1995.05.23 |
申请人 |
NOVO NORDISK A/S |
发明人 |
JONASSEN, IB;HAVELUND, SVEND;HANSEN, PER HERTZ;KURTZHALS, PETER;HALSTROEM, JOHN |
分类号 |
A61K38/00;A61K38/04;A61K38/22;A61K38/43;A61K47/48;C07K7/06;C07K14/00;C07K14/575;C07K14/58;C07K14/605;C07K14/655;C07K14/665;(IPC1-7):C07K7/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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