发明名称 PIPERAZINE DERIVATIVES
摘要 The invention relates to piperazine derivatives of formula (I), wherein R1, m, k and R2 have the meaning given in Claim 1. Said piperazine derivatives are potent 5-HT1A agonists, have 5-HT-re-uptake inhibiting effects and are suitable for treating and preventing anxiety states, depression, schizophrenia, obsessive thoughts, tardive dyskensia, learning impairments and memory disturbances caused by age, for positively influencing compulsive behaviour, and for treating and combating the effects of cerebral infarctions, such as strokes and cerebral ischaemia.
申请公布号 CA2296687(A1) 申请公布日期 1999.01.28
申请号 CA19982296687 申请日期 1998.06.29
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 发明人 BOETTCHER, HENNING;BARTOSZYK, GERD;SEYFRIED, CHRISTOPH;GREINER, HARTMUT
分类号 C07D405/14;A61K31/495;A61K31/496;A61P9/00;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P43/00;C07D405/12;(IPC1-7):C07D405/12 主分类号 C07D405/14
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