发明名称 |
Telomerase activity assays |
摘要 |
Telomerase activity in a sample can be measured using a two reaction protocol. The first reaction involves the formation of telomerase substrate extension products from a telomerase substrate. The second reaction involves replication of the telomerase substrate extension products and/or amplification of signal generated by a bound probe. The presence of telomerase activity in a human somatic tissue or cell sample is positively correlated with the presence of cancer and can be used to diagnose a disease or other conditions of medical interest, as well as the course of disease progression or remission in a patient.
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申请公布号 |
US5863726(A) |
申请公布日期 |
1999.01.26 |
申请号 |
US19960631554 |
申请日期 |
1996.04.12 |
申请人 |
GERON CORPORATION |
发明人 |
HARLEY, CALVIN BRUCE;KIM, NAM WOO;WEINRICH, SCOTT LAWRENCE |
分类号 |
A61K38/00;C12N5/00;C12N9/12;C12N15/10;C12P19/34;C12Q1/48;C12Q1/68;G01N33/574;(IPC1-7):C12Q1/68;C07H21/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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