| 发明名称 |
Phosphoramidate derivatives |
| 摘要 |
The present invention includes phosphoramidate derivatives, compositions containing the same, and methods of using them as NAALADase inhibitors, particularly for the treatment of glutamate abnormalities and associated nervous tissue insult in a animal and for treatment of prostate disease and prostate cancer by inhibition of NAALADase enzyme.
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| 申请公布号 |
US5863536(A) |
申请公布日期 |
1999.01.26 |
| 申请号 |
US19960778733 |
申请日期 |
1996.12.31 |
| 申请人 |
GUILFORD PHARMACEUTICALS INC. |
发明人 |
JACKSON, PAUL F.;SLUSHER, BARBARA S.;TAYS, KEVIN L.;MACLIN, KEITH M. |
| 分类号 |
A61K31/194;A61K38/05;A61K38/06;C07F9/30;C07F9/40;C07F9/44;C07F9/58;C07F9/655;(IPC1-7):A61K39/395 |
主分类号 |
A61K31/194 |
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代理人 |
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