| 摘要 |
The present invention relates to compounds of the formula <IMAGE> wherein HET is <IMAGE> (i) <IMAGE> (ii) and <IMAGE> (iii) m is an integer from 1 to 4; R1 and R2 are independently selected from the group consisting of linear or branched alkyl of 1 to 6 carbon atoms; and cycloalkyl or cycloalkylalkyl having 3 to 7 ring carbon atoms, the ring carbon atoms optionally substituted with one or more alkyl groups having 1 to about 4 carbon atoms each; X is a substituent selected from the group consisting of hydrogen, halogen, alkyl, alkoxy, alkoxyalkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, alkylthio, and alkylthioalkyl, wherein each of said alkyl moieties has from 1 to about 6 carbon atoms; and Y and Z are independently selected from the group consisting of hydrogen, alkoxy of about 1 to 6 carbon atoms and halogen; and pharmaceutical compositions containing a therapeutically effective amount of the compounds in combination with a pharmaceutically acceptable carrier and a method for treating diseases mediated by platelet activating factor.
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