| 发明名称 |
Arylheteroaryl inhibitors of farnesyl-protein transferase |
| 摘要 |
The present invention is directed to compounds which inhibit famesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting famesyl-protein transferase and the famesyl of the oncogene protein Ras.
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| 申请公布号 |
US5859035(A) |
申请公布日期 |
1999.01.12 |
| 申请号 |
US19970827486 |
申请日期 |
1997.03.27 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
ANTHONY, NEVILLE J.;GOMEZ, ROBERT P.;YOUNG, STEVEN D. |
| 分类号 |
C07D233/54;C07D233/70;C07D403/10;C07D403/14;C07D413/06;C07D417/06;(IPC1-7):A61K31/415;A61K31/41;A61K31/42;C07D275/06;C07D277/20;C07D261/06 |
主分类号 |
C07D233/54 |
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