Process for the production of the form I of the anhydrous terazosin monohydrochloride

摘要

The process for the production of form I of anhydrous terazosin monohydrochloride consists of heating terazosin suspended in a mixture made by methanol and a solvent selected from C2 to C6, straight or branched alcohols, esters of C1-C8 aliphatic carboxylic acids with straight or branched C1 to C8 alcohols, C3 to C8 aliphatic ketones, C4 to C8 straight branched or cyclic aliphatic ethers, aliphatic amides and aliphatic nitriles with a methanol solution of hydrochloric acid.