发明名称 New compounds
摘要 There are provided novel compounds of formula (I)including their 3,4-dihydropyrimidine tautomer form, wherein R1, R2, R3, R4, R5, X and n are as defined in the specification, and optical isomers and racemates thereof and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are antagonists of N-type neuronal calcium channels useful in the treatment of cerebrovascular ischaemia and pain.
申请公布号 ZA9805323(B) 申请公布日期 1999.01.11
申请号 ZA19980005323 申请日期 1998.06.18
申请人 ASTRA AKTIEBOLAG 发明人 EILEEN S. DOWNS;WILLIAM F. MICHNE;M EDWARD JR PIERSON
分类号 A61K31/505;A61K31/506;A61P9/00;A61P9/10;A61P25/04;A61P25/06;A61P25/18;A61P25/28;A61P43/00;C07D233/54;C07D239/20;C07D401/04;C07D401/12;C07D401/14;C07D403/12;C07D405/04;C07D405/14;C07D409/04;C07D409/14 主分类号 A61K31/505
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