发明名称 |
PROCESS FOR THE PRODUCTION OF DEXFENFLURAMINE HYDROCHLORIDE. |
摘要 |
Process for the production of the anorexic drug dexfenfluramine hydrochloride (INN) which comprises the ethylation of the (S),(S)-N-(1-phenylethyl)- alpha -methyl-3-(trifluoromethyl)benzeneethanamine or of a salt thereof with an organic or inorganic acid, the debenzylation of the resulting intermediate (S),(S)-N-ethyl-N-(1-phenylethyl)- alpha -methyl-3-(trifluoromethyl)benzeneethanamine or of a salt thereof with an organic or inorganic salt by catalytic hydrogenation and, optionally, the salification with hydrochloric acid.
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申请公布号 |
MX9709314(A) |
申请公布日期 |
1998.12.31 |
申请号 |
MX19970009314 |
申请日期 |
1997.12.01 |
申请人 |
ALFA CHEMICALS ITALINA S.R.L. |
发明人 |
VINCENZO CANNATA;STEFANO BIANCHI;ANGELO SPREAFICO;BARBARA MASPES |
分类号 |
B01J23/44;C07B61/00;C07C209/08;C07C209/68;C07C211/26;C07C211/29;C07C211/63;(IPC1-7):C07C211/53 |
主分类号 |
B01J23/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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