| 摘要 |
<p>A drug delivery system includes a container (174) in which a shock wave is generated for transmission to a target material, and a drug enhancement mechanism for enhancing absorption of a medicament by the target material. The container (174) includes a shock generating chamber (322), a shock tube (308) coupled to the shock generating chamber (322) having a membrane (310) mounted to a distal end through which the shock wave is transmitted, and a shock wave generating mechanism disposed within the shock generating chamber (322). Illustrative drug enhancement mechanisms include ultrasound, iontophoresis, high-pressure gradients, mechanical vibration, and surfactant. The shock generating mechanism may take various forms, including a rapidly openness divider and electric discharge.</p> |
