发明名称 A method of treating cancer
摘要 The present invention relates to methods of treating cancer using a combination of a compound which is an antineoplastic agent and a compound which is a inhibitor of prenyl-protein transferase, which methods comprise administering to said mammal, either sequentially in any order or simultaneously, amounts of at least two therapeutic agents selected from a group consisting of a compound which is an antineoplastic agent and a compound which is a inhibitor of prenyl-protein transferase. The invention also relates to methods of preparing such compositions.
申请公布号 AU7795798(A) 申请公布日期 1998.12.21
申请号 AU19980077957 申请日期 1998.06.04
申请人 MERCK & CO., INC.;SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH 发明人 NEAL ROSEN;LAURA SEPP-LORENZINO;MARK M. MOASSER;ALLEN I. OLIFF;JACKSON B GIBBS;NANCY KOHL;SAMUEL L. GRAHAM;GEORGE C. PRENDERGAST
分类号 C07D233/64;A61K31/198;A61K31/223;A61K31/4178;A61K31/4439;A61K31/495;A61K31/496;A61K31/497;A61K31/506;A61K35/00;A61K41/00;A61K45/06;A61P43/00;C07C323/25;C07D241/04;C07D307/33;C07D401/04;C07D401/06;C07D401/10;C07D401/14;C07D403/06;C07D403/10;C07D403/12 主分类号 C07D233/64
代理机构 代理人
主权项
地址