发明名称 Sphingoglycolipids, their preparation, and therapeutic methods of use
摘要 PCT No. PCT/JP93/01523 Sec. 371 Date Apr. 21, 1995 Sec. 102(e) Date Apr. 21, 1995 PCT Filed Oct. 22, 1993 PCT Pub. No. WO94/09020 PCT Pub. Date Apr. 28, 1994The present invention relates to a sphingoglycolipid represented by the following formula (I) which is effective at a small dose and has an anti-tumor activity and an immunostimulating effect with few side-effects: <IMAGE> (I) wherein X denotes an integer from 10 to 24, Y denotes an integer from 9 to 13, R1 represents a hexosyl, pentosyl, deoxyhexosyl, aminohexosyl, N-acetylaminohexosyl or a halide thereof or a sialic acid, R2 represents H or a group OR2', wherein R2' represents H or a galactosyl or glucosyl group, R3 represents H or a group OR3', wherein R3' represents H or a galactosyl or glucosyl group, R4 represents a galactosyl group or H, R5 represents a methyl or isopropyl group, R6 and R7 respectively represents H or form a double bond between the two carbon atoms to which R6 and R7 are attached, except for the case where R1 represents alpha -galactosyl and R4 represents H.
申请公布号 US5849716(A) 申请公布日期 1998.12.15
申请号 US19950416917 申请日期 1995.04.21
申请人 KIRIN BEER KABUSHIKI KAISHA 发明人 AKIMOTO, KOJI;KOEZUKA, YASUHIKO
分类号 C07H15/04;C07H15/10;(IPC1-7):A61K31/70;C07H15/00 主分类号 C07H15/04
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