发明名称 |
Animal model for hepatitis virus infection |
摘要 |
Chimeric mouse and rat models useful as models for human hepatitis virus (HV) infection are disclosed. These chimeras are made by substantially destroying the hematopoietic cells of a host mouse or rat and then transplanting into the resultant animal hematopoietic cells from SCID mice. The resultant chimera is then used as a host for transplantation of xenogeneic liver tissue, including liver tissue from humans. The liver tissue may be infected with HV either prior to or after transplantation.
|
申请公布号 |
US5849987(A) |
申请公布日期 |
1998.12.15 |
申请号 |
US19940242580 |
申请日期 |
1994.05.13 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD. |
发明人 |
REISNER, YAIR |
分类号 |
A01K67/027;A61K35/28;A61K35/38;A61K35/407;C07K16/10;(IPC1-7):C12N5/06;C12N15/09 |
主分类号 |
A01K67/027 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|