摘要 |
<p>The invention relates to the interaction between protein or peptide-coated microspheres and the αIIbβ3 receptor of activated platelets. Methods for identifying an antithrombocytopenic or putatively antithrombocytopenic composition by incubating a coated microsphere with activated human platelets and detecting phosphatidylinositol 4,5-biphosphate (PIP2) and phosphatidylinositol 4-phosphate (PIP) levels in the platelets are disclosed.</p> |