| 摘要 |
<p>The present invention discloses a transdermal drug delivery device comprising on a backing an adhesive layer, said adhesive layer comprising: (a) a copolymer of one or more A monomers and one or more B monomers, said A monomers being selected from the group consisting of alkylacrylates containing 4 to 12 carbon atoms in the alkyl group and alkylmethacrylates containing 4 to 12 carbon atoms in the alkyl group and said (B) monomers being hydrophilic monomers copolymerizable with said (A) monomers, and (b) a therapeutically effective amount of a drug selected from the group consisting of tropisetron and granisetron. The transdermal drug delivery device is suitable for the treatment of emesis and/or nausea or for the prevention of emesis and/or nausea. Further provided are pressure sensitive skin adhesives containing tropisetron or granisetron.</p> |
