发明名称 |
TUMOR NECROSIS FACTOR RECEPTOR-DERIVED PEPTIDE ANALOGUES |
摘要 |
The present invention relates to peptides and peptide analogues designed from a binding loop of a member of the tumor necrosis factor receptor (TNF-R) superfamily. In particular, it relates to cyclic peptides and peptide analogues designed from a binding loop of TNF-R which inhibit TNF binding to its cellular receptors, and methods of making and using such compounds to inhibit the biological activities of TNF.
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申请公布号 |
CA2291963(A1) |
申请公布日期 |
1998.12.03 |
申请号 |
CA19982291963 |
申请日期 |
1998.05.29 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
MURALI, RAMACHANDRAN;TAKASAKI, WATARU;GREENE, MARK I. |
分类号 |
A61K38/00;C07K7/50;C07K7/64;C07K14/705;(IPC1-7):A61K38/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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