| 发明名称 |
SYNTHESIS OF ACYCLIC NUCLEOSIDES |
| 摘要 |
<p>Compounds of the Formula Iwhere one of R1 and R2 is -C(O)CH(CH(CH3)2)NH2 or -C(O)CH(CH(CH3)CH2CH3)NH2;the other of R1 and R2 is -C(=O)C3-C21 saturated or monounsaturated, optionally substituted alkyl; andR3 is OH or H;and pharmaceutically acceptable salts thereof have utility as enhanced bioavailability antivirals against herpes and retroviral infections.</p> |
| 申请公布号 |
EP0880521(A1) |
申请公布日期 |
1998.12.02 |
| 申请号 |
EP19970903709 |
申请日期 |
1997.02.14 |
| 申请人 |
MEDIVIR AKTIEBOLAG |
发明人 |
ENGELHARDT, PER;HOEGBERG, MARITA;ZHOU, XIAO-XIONG;LINDBORG, BJOERN;JOHANSSON, NILS, GUNNAR |
| 分类号 |
C07D473/00;C07D473/18;(IPC1-7):C07D473/18;A61K31/52 |
主分类号 |
C07D473/00 |
| 代理机构 |
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代理人 |
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