| 摘要 |
A reservoir system for delivering an active agent into an oral cavity over an extended delivery period includes a pair of containers, which each have a hollow interior space for containing the active agent and at least one opening for dispensing the active agent, and a flexible plastic appliance for securing the containers within the oral cavity at a desired location. The containers are located within chambers formed in opposite sides of the appliance. The container includes a molded plastic body having a size and shape suitable for comfortably retaining the container within the oral cavity for the extended delivery time. The body is generally oval and cabochon-shaped to comfortably fit in the vestibule between the teeth/gums and cheek of the patient. The appliance is custom molded to closely fit the patient. The reservoir system can further include a foraminous medium for directly holding and dispensing an active agent at a desired treatment location within the oral cavity. The foraminous medium is preferably imbedded within the flexible plastic appliance.
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