| 发明名称 |
Peptidic phosphinyloxymethyl ketones as interleukin-1 beta -converting enzyme inhibitors |
| 摘要 |
Disclosed are compounds, compositions and methods for inhibiting interleukin -1 beta protease activity, the compounds having the structure of formula (1) as described in the specification.
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| 申请公布号 |
US5843905(A) |
申请公布日期 |
1998.12.01 |
| 申请号 |
US19960597346 |
申请日期 |
1996.02.06 |
| 申请人 |
VERTEX PHARMACEUTICALS, INCORPORATED |
发明人 |
SINGH, JASBIR;DOLLE, ROLAND E.;SPEIER, GARY |
| 分类号 |
A61K38/00;C07F9/32;C07F9/40;C07K5/06;(IPC1-7):A61K38/06;C07K5/00;C07K7/00 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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