发明名称 Use of inhibitors of cyclooxygenase in the treatment of neurodegenerative diseases
摘要 The present invention provides a method of treating a neurodegenerative disease and in particular Alzheimers disease which comprises administering to a human in need thereof a therapeutically effective amount of a non-steroid COX-II inhibitor. Although a wide range of COX-II inhibitors may be employed but it is preferred to employ compounds of the Formula I: <IMAGE> I
申请公布号 US5840746(A) 申请公布日期 1998.11.24
申请号 US19970926291 申请日期 1997.09.05
申请人 MERCK FROSST CANADA, INC. 发明人 DUCHARME, YVES;GAUTHIER, JACQUES YVES;PRASIT, PETPIBOON;LEBLANC, YVES;WANG, ZHAOYIN;LEGER, SERGE;THERIEN, MICHEL
分类号 A61K31/10;A61K31/341;A61K31/381;A61K31/425;A61K31/426;C07C311/08;C07C311/29;C07C311/46;C07C311/49;C07C317/24;C07C323/49;C07D209/26;C07D275/02;C07D277/26;C07D307/38;C07D307/58;C07D333/18;C07D333/38;C07D405/04;(IPC1-7):A61K31/38;A61K31/34;A61K31/27 主分类号 A61K31/10
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