发明名称 |
Forms of prostate specific antigen and methods for their detection |
摘要 |
Inactive precursor forms of PSA (pPSA) have been identified. At least one of these forms of pPSA exists in human serum. An expression vector is provided to stably express PSA, in the form of pPSA, in a mammalian system. Methods for detecting inactive precursors of PSA in human physiological fluid are provided. Antibodies specific for pPSA are also provided, as well as diagnostic kits and methods useful in the diagnosis and management of prostate cancer. |
申请公布号 |
AU7166898(A) |
申请公布日期 |
1998.11.24 |
申请号 |
AU19980071668 |
申请日期 |
1998.04.28 |
申请人 |
HYBRITECH INCORPORATED |
发明人 |
MOHAMMAD S SAEDI;STEPHEN D. MIKOLAJCZYK;ABHAY KUMAR;LANA S GRAUER;ROBERT L. WOLFERT;HARRY G. RITTENHOUSE |
分类号 |
G01N33/53;C07K16/18;C07K16/40;C12N5/10;C12N9/64;C12N15/09;C12N15/57;C12P21/02;C12P21/08;C12Q1/68;G01N33/574 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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