| 摘要 |
PCT No. PCT/AU94/00314 Sec. 371 Date Feb. 5, 1996 Sec. 102(e) Date Feb. 5, 1996 PCT Filed Jun. 10, 1994 PCT Pub. No. WO94/29461 PCT Pub. Date Dec. 22, 1994The present invention provides a method for the silencing of specific genes by DNA methylation. The method involves introducing into a cell a single stranded oligonucleotide containing 5-methyl deoxycytosine. The single stranded oligonucleotide has a sequence complementary to a portion of the DNA sequence of the gene to be silenced.
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