发明名称 Biodegradable compositions comprising poly(cycloaliphatic phosphoester) compounds, articles, and methods for using the same
摘要 Biodegradable, flowable or flexible polymer compositions are described comprising a polymer having the recurring monomeric units shown in formula I:wherein:each of R and R' is independently straight or branched alkylene, either unsubstituted or substituted with one or more non-interfering substituents;L is a divalent cycloaliphatic group;R'' is selected from the group consisting of H, alkyl, alkoxy, aryl, aryloxy, heterocyclic or heterocycloxy; andn is 5 to 1,000,wherein said biodegradable polymer is biocompatible before and upon biodegradation. In one embodiment, one or more of R, R' or R'' is a biologically active substance.Amorphous compositions containing a biologically active substance, in addition to the polymer, and methods for controllably releasing biologically active substances using the compositions, are also described.
申请公布号 AU7177198(A) 申请公布日期 1998.11.24
申请号 AU19980071771 申请日期 1998.04.30
申请人 GUILFORD PHARMACEUTICALS INC.;JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE 发明人 WENBIN DANG;HAI-QUAN MAO;IRINA SHIPANOVA-KADIYALA;KAM W LEONG;ZHONG ZHAO;JAMES P. ENGLISH
分类号 A61K47/30;A61K47/34;A61K47/48;A61L27/00;A61L27/18;A61L31/06;C08G79/04;C08K5/00;C08L85/02 主分类号 A61K47/30
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