| 发明名称 |
Humanized antibodies against leukocyte adhesion molecule VLA-4 |
| 摘要 |
The invention provides humanized immunoglobulins that specifically bind to the VLA-4 ligand, and methods of treatment using the same. The methods are particularly useful for treatment of multiple sclerosis.
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| 申请公布号 |
US5840299(A) |
申请公布日期 |
1998.11.24 |
| 申请号 |
US19950561521 |
申请日期 |
1995.11.21 |
| 申请人 |
ATHENA NEUROSCIENCES, INC. |
发明人 |
BENDIG, MARY M.;LEGER, OLIVIER J.;SALDANHA, JOSE;JONES, S. TARRAN;YEDNOCK, TED A. |
| 分类号 |
C12N15/09;A61K31/00;A61K38/00;A61K39/395;A61P1/00;A61P1/04;A61P3/00;A61P3/10;A61P7/00;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P13/00;A61P13/12;A61P17/00;A61P17/06;A61P25/28;A61P29/00;A61P35/00;A61P35/04;A61P37/00;C07H21/04;C07K;C07K16/18;C07K16/28;C07K16/46;C12N5/00;C12N5/10;C12N15/13;C12P21/08;C12R1/91;G01N33/53;(IPC1-7):A61K39/395 |
主分类号 |
C12N15/09 |
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