发明名称 |
TREATMENT OF PERIODONTAL DISEASE WITH ALENDRONATE |
摘要 |
<p>This invention claims a method for treating periodontal disease in mammals, including humans, by administering an effective amount of 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or a pharmaceutically acceptable salt including the monosodium salt tridydrate (alendronate) of the formula: <IMAGE> The compounds are useful in the treatment of alveolar bone loss associated with peridontitis and periodontal disease.</p> |
申请公布号 |
LV12084(B) |
申请公布日期 |
1998.11.20 |
申请号 |
LV19980000043 |
申请日期 |
1998.03.06 |
申请人 |
MERCK & CO., INC. |
发明人 |
GERTZ,BARRY, J.;RODAN,GIDEON, A. |
分类号 |
A61K31/66;A61P1/02;(IPC1-7):A61K31/66 |
主分类号 |
A61K31/66 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|