| 摘要 |
<p>Process for the removal of high-molecular particles from a process stream by means of ultrafiltration, wherein the ultrafiltration is performed in a unit comprising different stages, which different stages in the course of the ultrafiltration process are successively closed, drained and subjected to diafiltration and washing, the washing liquid leaving the one stage being used again in the next stage. By preference, the unit is set up such that maximum drainage is achieved, for instance by carrying out the drainage under pressure. In particular, the invention is applied to the reaction mixture obtained after enzymatic acylation of a beta -lactam core. <IMAGE></p> |
