发明名称 Novel antiatherosclerosis agents for lipid-lowering and antiperoxidative activity
摘要 Compounds of formula (I) wherein R 1 is hydrogen, hydroxy or alkoxy; each of R 2 , R 3 , R 4 and R 5 , which are the same or different, is hydrogen or alkyl; and n is 0, 1 or 2; and the pharmaceutically acceptable salts thereof; act as inhibitors of LDL-peroxidation and can therefore be used to treat or prevent atherosclerosis, hypercholesterolemia or hyperlipidemia. Also disclosed are pharmaceutical compositions containing compounds of formula (I) and a process for making such compounds.
申请公布号 GB2325223(A) 申请公布日期 1998.11.18
申请号 GB19970010149 申请日期 1997.05.16
申请人 * DEVELOPMENT CENTER FOR BIOTECHNOLOGY 发明人 FENG-WEN * YENG;SHAN-SHUE * WANG;JAW-YUH * CHIU;CHIN-FEN * LEE;CHIA-LIN J * WANG
分类号 A61K31/10;A61P3/06;A61P9/10;C07C315/02;C07C317/22;C07C319/14;C07C323/20 主分类号 A61K31/10
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