Peptides and antibodies for treatment of rheumatoid arthritis

摘要

PCT No. PCT/GB92/02174 Sec. 371 Date Jul. 28, 1994 Sec. 102(e) Date Jul. 28, 1994 PCT Filed Nov. 25, 1992 PCT Pub. No. WO93/11153 PCT Pub. Date Jun. 10, 1993A synthetic peptide of not more than 20 amino acid residues or analogue thereof comprising a thiol-active cysteine residue and at least two positively charged amino acid residues situated on (but not necessarily adjacent to) the N-terminal side, on (but not necessarily adjacent to) the C-terminal side or on (but not necessarily adjacent to) both the N- and C-terminal sides of the thiol-active cysteine for use in therapy.