PRODUCTION OF SUBSTITUTED HALOMETHYLPHENYLCARBAMIC ACID ESTERS

摘要

PROBLEM TO BE SOLVED: To enable the obtaining of the subject compound useful as an intermediate for insecticides in the agrochemical field from an inexpensive and readily handleable raw material at a low cost by halogenating a (substituted) tolyl carbamate. SOLUTION: (A) A compound represented by formula I [R is a 1-10C alkyl; R<1> is 1-4 substituent groups selected from hydrogen, a halogen and a 1-5C alkoxy(carbonyl)] is halogenated in the presence of (B) a catalyst such as a peroxide or an azobis-based compound and (C) a halogenating agent such as chlorine, bromine or an N-halosuccinimide to afford a compound represented by formula II (X is a halogen). The reaction is preferably carried out at 60-90 deg.C reactional temperature by using the component B in an amount of 0.1-5 wt.% based on the component A.