Improved preparation for colonic evacuation

摘要

The present invention relates to an osmotic colonic evacuant in solid oral dosage form comprising an orthostatic lavage in powder form and a pharmaceutically acceptable excipient, diluent and/or adjuvant. The present invention also relates to an osmotic colonic evacuant in powder form together with a diluent for use in a method of evacuating a patient's colon, a method of treating a small bowel bacterial overgrowth or irritable bowel syndrome, or a method of treating acute of chronic bacterial bowel infection. The present invention further relates to two or more osmotic colonic evacuants for use in sequential oral administration to a patient in two or more treatment regimens, wherein the first evacuant is in solid oral unit dosage form adapted and presented for a first administration period and the second evacuant is in solid oral unit dosage form adapted and presented for a second administration period.