发明名称 HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS
摘要 The present invention relates to antithrombotic compounds comprising the group Q, Q having formula (I), wherein the substructure (i) is a structure selected from (a, b and c), wherein X is O or S; X' being independently CH or N; and m is 0, 1, 2 or 3; wherein the group Q is bound through an oxygen atom or an optionally substituted nitrogen or carbon atom, or a pharmaceutically acceptable salt thereof or a prodrug thereof. The compounds of the invention are therapeutically active and in particular are antithrombotic agents.
申请公布号 WO9847876(A1) 申请公布日期 1998.10.29
申请号 WO1998EP02455 申请日期 1998.04.21
申请人 AKZO NOBEL N.V.;VAN BOECKEL, CONSTANT, ADRIAAN, ANTON;VAN GALEN, PHILIPPUS, JOHANNES, MARIE;REWINKEL, JOHANNES, BERNARDUS, MARIA 发明人 VAN BOECKEL, CONSTANT, ADRIAAN, ANTON;VAN GALEN, PHILIPPUS, JOHANNES, MARIE;REWINKEL, JOHANNES, BERNARDUS, MARIA
分类号 A61K31/38;A61K31/4355;A61K31/4436;A61K31/444;A61K31/47;A61K31/4709;A61K31/472;A61K31/5355;A61K38/00;A61P7/02;C07D217/22;C07D401/06;C07D401/12;C07D405/12;C07D405/14;C07D413/12;C07D413/14;C07D491/04;C07D491/048;C07D495/04;C07K5/02;C07K5/06;C07K5/062;C07K5/065;C07K5/072;C07K5/078;(IPC1-7):C07D217/22 主分类号 A61K31/38
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