发明名称 PHARMACEUTICAL COMPOSITIONS FOR IMMUNOSUPPRESSION, ANTICANCER AND ANTIVIRAL TREATMENT
摘要 Compounds and uses thereof for the preparation of pharmaceutical compositions as immunosuppressants, anticancer agents, and antiviral agents, the compound having formula (IV) where R is H, PO3<=>, alkyl of 1 to 12 carbon atoms substituted or unsubstituted, straight chain or branched, 0 to 6 double bonds, (CH2)nmorpholine where n=1-4, morpholinomethylphenyl, orthoaminophenyl, orthohydroxyphenyl, (CH2)nCOOR2 where n=1-4; where R2 is H, an alkalai metal salt, an alkaline earth metal salt, NH4<+>, N<+>(R3)4, where R3 is independently selected from the group consisting of H and alkyl of 1 to 4 carbon atoms, COR1 wherein R1 is selected from the group consisting of H, (CH2)nCH3, where n=0-6, (CH2)nCOOR2 where n=1-4 and R2 is previously defined, (CH2)nN<+>(R3)4 wherein n=1-4, and (CH2)nSO3<-> where N=1-4.
申请公布号 WO9846222(A1) 申请公布日期 1998.10.22
申请号 WO1998US08013 申请日期 1998.04.15
申请人 IMMUNE MODULATION, INC. 发明人 OJO-AMAIZE, EMMANUEL, A.;OKOGUN, JOSEPH, I.;COTTAM, HOWARD, B.;KAKKANAIAH, VELLALORE, N.
分类号 C07D303/06;A61K31/336;A61K38/21;A61P31/12;A61P31/18;A61P31/22;A61P35/00;A61P37/06;C07D493/08;(IPC1-7):A61K31/335 主分类号 C07D303/06
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