发明名称 METHOD OF TREATING RESTENOSIS BY ANTISENSE TARGETING OF CMV
摘要 A method of inhibiting restenosis in a CMV-infected subject undergoing, or having undergone, angioplasty or atherectomy is described. The subject is treated, preferably at the site of the operation, with an oligomeric molecule effective to specifically hybridize to all or part of a target nucleic acid sequence derived from a human cytomegalovirus (HCMV) gene. The oligomeric molecule is preferably a morpholino oligomer composed of morpholino subunits, each containing a purine or pyrimidine base-pairing moiety, joined by phosphoramidate linkages.
申请公布号 WO9846740(A1) 申请公布日期 1998.10.22
申请号 WO1998US07866 申请日期 1998.04.16
申请人 ANTIVIRALS, INC. 发明人 BURGER, DENIS, R.
分类号 A61K38/00;C12N15/113;(IPC1-7):C12N15/11;A61K31/70;A61L29/00;A61M25/10;C07H21/00 主分类号 A61K38/00
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