摘要 |
A method of inhibiting restenosis in a CMV-infected subject undergoing, or having undergone, angioplasty or atherectomy is described. The subject is treated, preferably at the site of the operation, with an oligomeric molecule effective to specifically hybridize to all or part of a target nucleic acid sequence derived from a human cytomegalovirus (HCMV) gene. The oligomeric molecule is preferably a morpholino oligomer composed of morpholino subunits, each containing a purine or pyrimidine base-pairing moiety, joined by phosphoramidate linkages.
|