发明名称 5, 6, 7-Trisubstituted-4-aminopyrido (2, 3-d) pyrimidine compounds
摘要 A compound having formula (II) wherein R<1>, R<2>, R<3>, R<4> and R<5> are defined, a method for inhibiting adenosine kinase by administering a compound thereof, a pharmaceutical composition comprising a therapeutically effective amount of a compound thereof above in combination with a pharmaceutically acceptable carrier, a method of treating cerebral ischemia, epilepsy, pain, nociperception, inflammation and sepsis in a mammal in need of such treatment, comprising administering to the mammal a therapeutically effective amount of a compound thereof, and methods for preparation thereof.
申请公布号 ZA9803175(B) 申请公布日期 1998.10.21
申请号 ZA19980003175 申请日期 1998.04.15
申请人 ABBOTT LABORATORIES 发明人 SHRIPAD S. BHAGWAT;RICHARD J. PERNER;YU-GUI GU
分类号 A61P25/04;A61K31/519;A61P1/00;A61P3/10;A61P9/00;A61P25/08;A61P25/18;A61P25/22;A61P29/00;A61P31/00;A61P37/06;A61P43/00;C07D471/04 主分类号 A61P25/04
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