Methods of preparing interdigitation-fusion liposomes and gels which encapsulate a bioactive agent
摘要
This invention provides a composition containing a sized liposome comprising a lipid and an induce; the sized liposome has a diameter of at most about 1 micoron and the induces is present in an amount effective to induce interdigitation-fusion of the sized liposome. Also provided herein are interdigitation-fusion liposomes and gels, and methods of making the same.
申请公布号
US5820848(A)
申请公布日期
1998.10.13
申请号
US19940315988
申请日期
1994.09.30
申请人
THE LIPOSOME COMPANY, INC.
发明人
BONI, LAWRENCE T.;JANOFF, ANDREW S.;MINCHEY, SHARMA R.;PERKINS, WALTER R.;SWENSON, CHRISTINE E.;AHL, PATRICK L.;DAVIS, THOMAS S.