发明名称 Microspheres of diamide-dicarboxylic acids
摘要 Diamide-dicarboxylic acid microspheres are provided. The diamide-dicarboxylic acids may be combined with active agent(s). The resultant composition may be in microsphere form. Also disclosed are methods for administering the microsphere and/or composition that includes the active agent. The microsphere, with or without active agent, may be prepared by (A) solubilizing, in a solvent, at least one diamide-dicarboxylic acid, to yield a first solution; and (B) contacting the first solution with a precipitator solution in which the diamide-carboxylic acid is insoluble and optionally with an active agent.
申请公布号 US5820881(A) 申请公布日期 1998.10.13
申请号 US19950430491 申请日期 1995.04.28
申请人 EMISPHERE TECHNOLOGIES, INC. 发明人 MILSTEIN, SAM J.
分类号 A61K9/16;B01J13/02;C07C235/74;C07C235/76;C07C235/78;(IPC1-7):A61K9/16;A61K47/12;C07C229/00 主分类号 A61K9/16
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