| 发明名称 |
CHEMOKINE BETA-6 |
| 摘要 |
Human chemokine .beta.-6 agonist and antagonist polypeptides and DNA encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques are disclosed. The chemokine .beta.-6 antagonists of the present invention may be employed to treat rheumatoid arthritis, lung inflammation, allergy, asthma, infectious diseases and to prevent inflammation and atherosclerosis. The chemokine .beta.-6 agonists may be employed to myeloprotect patients undergoing chemotherapy.
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| 申请公布号 |
CA2285622(A1) |
申请公布日期 |
1998.10.08 |
| 申请号 |
CA19982285622 |
申请日期 |
1998.03.31 |
| 申请人 |
THEODOR KOCHER INSTITUTE;HUMAN GENOME SCIENCES, INC. |
发明人 |
OLSEN, HENRIK S.;RUBEN, STEVEN M.;BAGGIOLINI, MARCO;KREIDER, BRENT L. |
| 分类号 |
C12N15/09;A61K38/00;A61K48/00;A61P9/10;A61P11/00;A61P11/06;A61P29/00;A61P31/00;A61P37/08;C07K14/52;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12N15/19;(IPC1-7):C12N15/19;A61K49/00;A61K38/19;G01N33/50;C12Q1/68;G01N33/84;G01N33/88 |
主分类号 |
C12N15/09 |
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