| 摘要 |
<p>Novel 1,4-substituted cyclic amine derivatives which have serotonin antagonism and serve as drugs having high clinical usefulness, especially an agent for the remedy/alleviation/prevention of spastic paralysis or a central muscle relaxant for alleviating myotonia. The derivatives are represented by general formula (I) or pharmacologically acceptable salts thereof, wherein A, B, C, D, T, Y, and Z each represents a methine group or a nitrogen atom; R?1, R2, R3, R4, and R5¿ each represents a substituent; n is an integer of 0 to 3; m is an integer of 0 to 6; and p is an integer of 1 to 3.</p> |
