发明名称 |
Basic protein composition, basic peptide composition and application thereof |
摘要 |
The present invention can provide a basic protein and/or a basic peptide composition which can be orally taken and has action of simulating osteoblastic proliferation, strengthening bone and inhibiting bone resorption. Said basic protein has the following properties: (1) the molecular weight distribution thereof is 2,000-24,000; (2) the isoelectric point thereof is 7.5-11; and (3) it comprises more than 10% of basic amino acids as composing amino acids. Said composition can be obtained by the following steps: After milk or raw material derived from milk is loaded on a cation exchange resin column, a fraction obtained by eluting with an eluent of 0.1-1.0M salt concentration is precipitated by heating over 75 DEG C, (ii) by adding alcohol so that the final concentration thereof will be 10-50% or (iii) by adding salts so that the final concentration thereof will be more than 0.2M; and the supernatent thereof can be recovered. <IMAGE> |
申请公布号 |
EP0786473(A3) |
申请公布日期 |
1998.10.07 |
申请号 |
EP19970100945 |
申请日期 |
1997.01.22 |
申请人 |
SNOW BRAND MILK PRODUCTS CO., LTD. |
发明人 |
TAKADA, YUKIHIRO;AOE, SEIICHIRO;MATSUYAMA, HIROAKI;KATO, KEN;YAMAMURA, JUNICHI |
分类号 |
A21D2/26;A23C9/146;A23C19/08;A23C19/082;A23J1/20;A23J3/08;A23J3/34;A23K1/16;A23K1/18;A23L1/06;A23L1/305;A23L2/66;A61K31/00;A61K38/00;A61K38/01;A61P3/02;A61P7/00;A61P19/00;A61P37/00;A61P43/00;C07K1/12;C07K1/18;C07K1/34;C07K14/47;C07K14/51;C12S3/24 |
主分类号 |
A21D2/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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