New oxazolidine derivatives processes for their production and pharmaceutical agents containing these compounds

摘要

Oxazolidinone compounds of formula (I) and their salts are new. X = H or NR1R2; W, Q, Y = N or CH; Z = N, CH or C-OH; A = bond or optionally substituted (CH2)p; D = COOH, CH(R3)COOH or =C(R3)COOH; n, p = 1-3; m = 0 or 1; R1, R2 = H, lower alkyl, aryl, arylalkyl, heteroaryl, acyl or an optionally substituted carbocyclic or heterocyclic ring; or NR1R2 = C(R0)=NH or an optionally substituted 5 or 6 membered heterocycle (optionally containing 1-3 additional heteroatoms); R3 = H, OR5 or NR6R7; R4 = H or OR5; R5 = H, lower alkyl, aryl or arylalkyl; R6 = H, lower alkyl or arylalkyl; R0 = H, lower alkyl, arylalkyl or NHR00; and R7, R00 = H, lower alkyl, arylalkyl, acyl, alkylsulphonyl or arylsulphonyl.