Process for producing calcium salt of (-)-Erythrohydroxycitric acid

摘要

A process for extraction of hydroxycitric acid as calcium salt from the fruit rind of Garcinia species such as Garcinia cambogia, Garcinia indica and Garcinia atroviridis, which comprises reaction of an aqueous suspension of Garcinia rind with a mixture of pectic enzymes such as polygalactouronase (PG) and pectin lysase (PL), at a temperature of 40 DEG C followed by addition of an alkali such as sodium hydroxide and, from the intermediate alkali metal salt of hydroxycitric acid the corresponding calcium salt is prepared by addition of calcium chloride. The calcium salt of (-)-hydroxycitric acid is therapeutically active component.