| 摘要 |
The use of compounds of formula I as topical agents to combat the disorders of the skin, produced by photodamage, which disorders include wrinkling, elastosis and premature aging is described. Compounds of formula I are <IMAGE> I wherein R is hydrogen, fluorine, or hydroxy, R2 is hydrogen, lower alkyl or halogen, X is =CH2 or when R is hydroxy X is hydrogen or =CH2, <IMAGE> -CH2-CH2-, provided that when A is -CH2-CH2-, R2 is hydrogen or lower alkyl.
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