发明名称 Verwendung von anti-CD44 Antikörpern enthaltenden Präparationen zur Behandlung bestimmter Tumore und zur Unterdrückung von Immunreaktionen
摘要 The present invention relates to the use of anti-CD44 antibodies from the constant portion (sDC44) and variable portion of CD44 (VCD44) in the treatment of certain tumours and other diseases which are associated with degeneracy and activation of Langerhans cells (LC) and dendritic cells (DC) in the body of a mammal including human beings, and in the treatment of undesirable immune reactions. The invention also relates to an ex vivo culture method for the production of dendritic cells.
申请公布号 DE19708713(A1) 申请公布日期 1998.09.17
申请号 DE19971008713 申请日期 1997.03.04
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH, 55218 INGELHEIM, DE;FORSCHUNGSZENTRUM KARLSRUHE GMBH, 76133 KARLSRUHE, DE 发明人 HERRLICH, PETER, PROF. DR., 76229 KARLSRUHE, DE;PONTA, HELMUT, PROF. DR., 76356 WEINGARTEN, DE;SIMON, JAN, DR., 79249 MERZHAUSEN, DE;WEISS, JOHANNES, DR., 79183 WALDKIRCH, DE
分类号 C12N5/06;A61K38/00;A61K39/395;A61P17/06;A61P29/00;A61P37/06;A61P37/08;C07K16/28;C12N5/22;(IPC1-7):A61K39/395;C12N5/16 主分类号 C12N5/06
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