| 发明名称 |
HIPOLIPIDEMAT 1,4-BENZOTIAZEPIN-1,1-DIOKSIDA |
| 摘要 |
The present invention is concerned with new hypolipidemic compounds (I) and with their use in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions, such as atherosclerosis. Compounds of the formula (I): <CHEM> wherein X is -NH- or -O-; and R<7> is a group of the formula <CHEM> wherein the hydroxyl groups may be substituted by acetyl or benzyl, or -(C1-C6)-alkyl-R<17> wherein the alkyl group may be substituted with one or more hydroxyl groups; R<16> is -COOH or -CH2-OH; R<17> is H, -OH, -NH2, -COOH or COOR<18>; R<18> is (C1-C4)-alkyl or -NH-(C1-C4)-alkyl. |
| 申请公布号 |
ID20053(A) |
申请公布日期 |
1998.09.17 |
| 申请号 |
ID19980000360 |
申请日期 |
1998.03.12 |
| 申请人 |
HOECHST AKTIENGESELLSCHAFT |
发明人 |
DR. ALFONS ENHSEN;DR. EUGEN FALK;DR. HEINER GLOMBIK;DR. SIEGFRIED STENGELIN |
| 分类号 |
C12N15/09;A61K31/55;A61K31/554;A61K31/675;A61K31/70;A61K48/00;A61P1/16;A61P3/06;A61P3/10;A61P9/10;A61P35/00;C07D281/00;C07D281/10;C07D417/04;C07D417/10;C07D417/12;C07F9/6558;C07H17/00;C12N5/00;C12N5/10;C12N9/12;C12N15/06;C12N15/10;C12N15/11;C12N15/54;C12N15/85;C12P21/02;C12R1/91 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
