发明名称 STABILIZATION OF TRANSFERRIN RECEPTOR
摘要 PROBLEM TO BE SOLVED: To stabilize a transferrin receptor (TfR) used for a reagent for measuring the TfR in blood, which is an indicator of a cancer, a hematopoietic system, etc., by adding an albumin and saccharides to the TfR, a transferrin-TfR complex, etc. SOLUTION: The objective transferrin receptor (TfR) used as a standard material, etc., for immunological analysis of the TfR in blood which is an indicator of a cancer, a hematopoietic system, etc., is stabilized so that reliability as the standard material may be improved by preventing the decrease of a measured value of the TfR accompanied by refrigeration and defrost, by formulating TfR or a transferrin-TfR complex (TRC) with an albumin such as bovine serum albumin, and saccharides such as sucrose, fructose, lactose, maltose and trehalose, forming the formulated materials into a liquid by adding a physiological saline or a buffer thereto, regulating the pH of the solution so as to be 6-9, and further, regulating the concentration of the albumin so as to be 0.5-30% W/V.
申请公布号 JPH10245400(A) 申请公布日期 1998.09.14
申请号 JP19970062516 申请日期 1997.02.28
申请人 EIKEN CHEM CO LTD 发明人 YASUNAKA TOSHIMITSU;TOIKAWA AKIHISA
分类号 G01N33/53;A61K35/16;A61K38/00;C07K14/705;G01N33/531 主分类号 G01N33/53
代理机构 代理人
主权项
地址